Individuals and Patients

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Are you having challenges with your current medication therapy? Do you want to make sure the prescriptions you depend on really are right for you? Or are you curious what medications may work best for you? Ready to live a healthier life with fewer trips to the doctor? It’s time for ExactMeds®.

With ExactMeds®, we can take a close, personal look at what medications are safest and most appropriate, just for you. If you're ready to order, just click the button and we will be in touch to help you get started. An easy at-home collection kit will be sent to you and, when your results are in, a certified pharmacist will contact you to discuss the results and exactly what they mean for you and your healthcare.

* FSA/HSA Eligible

Each individual is unique and deserves to be treated like it. ExactMeds® could show your healthcare team just how to do that.

Pharmacogenomics considers an individual’s genetics relative to what impact they have on how their bodies process medications. A medication that may be beneficial for one person may be dangerous for another, just based on slight differences in their genes. Taking a look inside will help take the guesswork out of prescribing for you.

The Right Medication
Failure rates for classes of medications can be as high as 75% and genetic factors can account for up to 95% of this variability. Virtually every test shows a genetic variance that could affect how your body metabolizes particular medications. A pharmacogenomic (PGx) test, followed by a consultation by a PGx-trained pharmacist, could be a good first step toward better results.

The Only Way to Know 
With many medications, it’s difficult to tell whether or not it’s actually working for you. A quick test, using just a quick cheek swab, is the only way to tell you if the medication you’re on is right for your genes and has a chance of being effective for you. That’s always a good place to start.

Where Does It Help?
While the science behind PGx testing does not yet apply to all medications on the market, there are several classes of medications where testing to create more personalized prescribing could have significant benefits, including with cardiac, behavioral health and pain medications. Success with these medications is critical and, without testing, may require trial-and-error before finding a solution.

Additional Information

Our cutting-edge technology solution gives us the ability to exchange health information and provide clinical decision support in real time. Test results are stored for the long-term, giving providers and patients the ability to reference medication insights across the entire healthcare system for a lifetime.


2.2 million serious adverse events occur per year, according to a report published by the Journal of the American Medical Association. These ADEs lead to approximately 1.3 million emergency room (ER) visits per year, and $3.5 billion excess spend of medical costs. [1]

1 – National Human Genome Institute  – National Institutes of Health (NIH)

Some of the more common conditions treated by these medications include, but are not limited to:

  • Chronic or acute pain
  • blood pressure (elevated)
  • depression
  • anxiety
  • other mental health conditions
  • diabetes
  • cholesterol (elevated)
  • cancer
  • arthritis
  • acid reflux
  • peptic ulcer
  • acid reflux
  • migraines
  • thyroid disorders
  • asthma/COPD
  • heart attack

Some commercial insurance plans offer coverage for testing, but not all. Medicare also offers coverage for patients who qualify. 

The Food and Drug Administration (FDA) currently has pharmacogenomic information listed in the package labeling of more than 250 medications, including many of the most prescribed, and this number continues to grow. Testing can apply to prescription medications, over-the-counter medications, herbal supplements, nutraceuticals and recreational medications. 

A signed order is required to process a test. This can be approved by an MD, DO, nurse practitioner or physician’s assistant. In some states, pharmacists may also order this and other tests.

RxGenomix is not a laboratory, but rather a PGx services company. RxGenomix partners with clinical testing laboratories that are accredited by the College of American Pathologists and meet the certification requirements for high complexity testing established under the Clinical Laboratory Improvement Amendments. RxGenomix then works with pharmacists and other healthcare providers to help them integrate the PGx testing process into their practice and provide enhanced clinical services to their patients.  

Until recently, medications have been developed with the idea that each drug works pretty much the same in everybody. However, genomic research has changed that “one size fits all” approach and opened the door to more personalized approaches to using and developing medications.

Depending on your genetic makeup, some medications may work more or less effectively for you than they do in other people. Likewise, some medications may produce more or fewer side effects in you than in someone else. As this science continues to evolve, healthcare providers will be able to routinely use information about your genetic makeup to choose those medications and drug doses that offer the greatest chance of helping you. 

PGx may also help to save you time and money. By using information about your genetic makeup, healthcare providers may be able to avoid the trial-and-error approach of giving you various medications that are not likely to work for you until they find the right one. UsingPGx, the “best-fit” drug to help you can be chosen from the beginning.

Pharmacogenomics (PGx) uses information about a person’s genetic makeup, or genome, to choose the medications and drug doses that are likely to work best for that particular person. This new field combines the science of how medications work, called pharmacology, with the science of the human genome, called genomics.

Each human being has some 30,000 genes in their DNA. Our current PGx testing looks at just 45 of those. That’s it. We’re only testing for variations in these few genes that affect how your body processes medications, or doesn’t.

Our testing produces a report that tells us if the genes responsible for putting a medication to work in your body are functioning properly. If they’re not, a common drug that’s safe for most could be ineffective or even dangerous for you. PGx testing is really the only way to know this before you begin taking a drug.

The test itself is painless and non-invasive, taking only a minute or two. The sample is collected by rubbing a swab inside each cheek for about 30 seconds and sending it off to the lab. That’s all there is to it.

Nearly every test returns information that could, at some point, be beneficial to you, your physician, and your pharmacist. While this does not necessarily mean a PGx test will be relevant to a medication you are currently taking, nearly everyone tested will have a variation in their genes that applies to how your body processes medications.

RxGenomix respects your privacy, and that includes your genetic information. Even though this testing will only look at a very small set of genes limited to drug metabolism, only those involved in delivering the best healthcare for you will have access to this information and it will be used solely to create a more personalized medication plan for you. For more information, you can read about our complete privacy practices here.

Genes tested include, but aren’t limited to, the Cytochrome P450 enzymes—CYP2D6, CYP2C9, CYP2C19, CYP3A4/5, and others. Other proteins, such as VKORC1 and SLCO1B1 represent drug targets and transporters, respectively. Click here for a complete list of genes tested.

In the metabolism of drugs, an individual can be classified in one of five categories (metabolism phenotype) for each gene, based on the activity of these pharmacogenomic proteins as defined by the Clinical Pharmacogenetics Implementation Consortium (CPIC):

Normal (formerly extensive metabolizer) (NM/EM)

  • Fully functional enzyme activity.

Intermediate metabolizer (IM)

  • Decreased enzyme activity (activity between normal and poor metabolizer).

Poor Metabolizer (PM)

  • Little to no enzyme activity.

Rapid/Ultrarapid Metabolizer (UM)

  • Increased enzyme activity compared to normal metabolizers.

By considering an individual’s genetics relative to drug metabolizing enzymes, targets, receptors and transporters, healthcare providers can now apply this information to prescribing for optimal drug therapy.

RxGenomix’s pharmacogenomic reports include genetic health risk information that has not been reviewed by the FDA. The ExactMeds®pharmacogenomic service leverages advanced genotype data to identify clinically relevant variants via patient saliva DNA for the purpose of understanding one’s health risk via medication utilization. The ExactMeds® program is not intended to diagnose any disease. A patient’s ethnicity may affect the relevance of each report and how one’s genetic health risk results are interpreted. Information delivered via the ExactMeds® service is not intended for a patient to independently act upon a medical decision, but rather to inform and provide the genetic risk information to share directly with their licensed provider.  The ExactMeds® pharmacogenomic reports are not intended to tell a patient anything about their risk for developing a disease in the future.  

The ExactMeds® pharmacogenomic service utilizes genotyping data to identify medication risk factors for the purpose of reporting and interpreting to inform discussions with a healthcare professional.  The ExactMeds® pharmacogenomic report provides certain information about variants associated with metabolism of some therapeutics and provides interpretive drug information regarding the potential effect of those medications. 

Warning: Pharmacogenomic test results should not be used to start, stop, or change any course of treatment without consulting with a patient’s provider. The ExactMeds® pharmacogenomic service is not a substitute for an appointment with a patient’s healthcare professional. For important information and limitations regarding pharmacogenomic testing, please visit: How Pharmacogenomics (PGx) Works - RxGenomix